Fig. 6.  (A ) Representative trace depicting the effect of the specific transient receptor potential ankyrin subtype-1 (TRPA1) activator allyl isothiocyanate (AITC; 100 μM) after capsaicin-induced (100 nM) desensitization on restoration of transient receptor potential vanilloid receptor subtype-1 (TRPV1) sensitivity in F-11 cells transfected with TRPV1 complementary DNA (cDNA) only. The dashed line indicates the statistical comparison that was made. (B ) Summarized data depicting the effect of AITC after capsaicin-induced desensitization on restoration of TRPV1 sensitivity in F-11 cells transfected with TRPV1 cDNA only. Data are expressed as a percentage of the response to the final application of capsaicin before AITC treatment (Control) and reported as the mean ± SD. (Four separate coverslips of F-11 cells were used.)