Fig. 3. Sequestration of polymorphonuclear neutrophils (PMN) within the coronary system. 20 min warm no-flow ischemia followed by 10 min reperfusion significantly increased the adhesion from control nonischemic conditions. Application of sevoflurane (Sevo) concentrations of 0.5 or 1 minimum alveolar concentration (MAC) significantly reduced adhesion of PMN in postischemic hearts to near the level obtained under control conditions. *P < 0.01 I/R (group M) versus Control groups (group D, E, and F). #P < 0.05 I/R + Sevo 0.5 (group N) and 1.0 MAC (group O) versus I/R (group M). I/R = ischemia-reperfusion.