Fig. 5. Significant effect of losartan treatment on subcongenic line 3a of the SS.13BNconsomic rat strain compared with the Dahl Salt Sensitive parental rat strain (SS/JrHsdMcwi, abbreviated as SS). (A ) The greater mean ± SD infusion rate of propofol required to reduce mean arterial blood pressure by 50% in untreated line 3a animals compared with losartan-treated line 3a animals and treated as well as untreated SS animals. (B ) The significantly attenuated change in Emof small mesenteric arterial vascular smooth muscle in untreated line 3a animals compared with losartan-treated line 3a animals and treated as well as untreated SS animals. *P ⩽ 0.05 versus all other groups, n = 6 animals per group.