Fig. 4. Expression of catalepsy caused by antipsychotics in mice. Catalepsy values were obtained for 60 min after subcutaneous injection of antipsychotics. The time until the forepaw touched the floor or until the mouse climbed up on the bar was measured for as long as 60 s. A score was assigned to each test based on the duration of the cataleptic posture (score 1, 15 to 29 s; score 2, 30 to 59 s; score 3, 60 s or more). Each column represents the mean ± SEM of six mice. Statistical analyses were performed with one-way ANOVA followed by the Bonferroni multiple comparisons test: F(12,77)= 12.59, P < 0.0001. *P < 0.05, **P < 0.01, or ***P < 0.001 versus vehicle.