Fig. 7. Blood glucose concentrations after chronic treatment with olanzapine. Hyperglycemia was not observed in treatment with olanzapine (0.03, 0.1, or 0.3 mg/kg subcutaneous injection) for 7 days, whereas the glucose concentration was significantly increased by subcutaneous injection of olanzapine at 1 mg/kg. Values are expressed as a percentage of the control. Each column represents the mean ± SEM of four mice. Statistical analyses were performed with one-way ANOVA followed by the Bonferroni multiple comparisons test. *P < 0.05 versus vehicle.