Fig. 6. Single-patient bispectral index (BIS) and end tidal anesthetic concentration (ETAC) in age-adjusted minimum alveolar concentration (aaMAC) equivalents over time (A , C , and E ) and BIS-aaMAC relationship (B , D , and F ). Patients were selected from those whose pharmacokinetically-censored data were over a more than 0.5 aaMAC range on the basis of their BIS-aaMAC slope in context of population characteristics. Patient A (A  and B ), −31 BIS units per 1 aaMAC increase (25thpercentile for slope). Patient B (C  and D ), −9 BIS units per 1 aaMAC increase (median slope). Patient C (E  and F ), −0.3 BIS units per 1 aaMAC increase (75thpercentile for slope). ASAPS = American Society of Anesthesiologists physical status; CABG = coronary artery bypass graft.

Fig. 6. Single-patient bispectral index (BIS) and end tidal anesthetic concentration (ETAC) in age-adjusted minimum alveolar concentration (aaMAC) equivalents over time (A , C , and E ) and BIS-aaMAC relationship (B , D , and F ). Patients were selected from those whose pharmacokinetically-censored data were over a more than 0.5 aaMAC range on the basis of their BIS-aaMAC slope in context of population characteristics. Patient A (A  and B ), −31 BIS units per 1 aaMAC increase (25thpercentile for slope). Patient B (C  and D ), −9 BIS units per 1 aaMAC increase (median slope). Patient C (E  and F ), −0.3 BIS units per 1 aaMAC increase (75thpercentile for slope). ASAPS = American Society of Anesthesiologists physical status; CABG = coronary artery bypass graft.

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