Fig. 4. Protein kinase Cα (A ), β (B ), γ (C ), and δ (D ) knockout mice have no statistically significant differences in complete Freund's adjuvant (CFA)-induced mechanical allodynia compared with wild-type littermate control mice. For all experiments, the experimenter was blind to genotype of the animals. ipsi = measurements were taken from the paw ipsilateral to the injection of CFA; KO = knockout; WT = wild type.