Fig. 2. Fluorescence photomicrographs of immunostaining of lysosome-associated membrane glycoprotein 1 (LAMP1), an activated mast cell marker in dermis of hind paw skin 4 weeks postfracture. In control skin, active mast cells are absent in the dermis (A ), whereas the large numbers of active mast cells were observed in the ipsilateral hind paw dermis at 4 weeks postfracture (B ). Scattered activated mast cell profiles were observed in the dermis of skin from paws contralateral to fracture (C ). ctrl = contralateral; ipsi = ipsilateral. Scale bar = 20 μm.