Fig. 5. Effects of gabapentin and L-isoleucine on 25 mM KCl-evoked γ-amino butyric acid (GABA) release in synaptosomes prepared from the lumbar spinal dorsal horn. Data are presented as percentage change from baseline release. Synaptosomes from normal (A ) and spinal nerve ligated (SNL: B ) rats were treated with buffer, gabapentin (GBP, 1–100 μM), or L-isoleucine (L-ILe, 10 μM). N = 6–15.

Fig. 5. Effects of gabapentin and L-isoleucine on 25 mM KCl-evoked γ-amino butyric acid (GABA) release in synaptosomes prepared from the lumbar spinal dorsal horn. Data are presented as percentage change from baseline release. Synaptosomes from normal (A ) and spinal nerve ligated (SNL: B ) rats were treated with buffer, gabapentin (GBP, 1–100 μM), or L-isoleucine (L-ILe, 10 μM). N = 6–15.

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