Fig. 3. (A ) Lung edema formation as measured by lung wet/dry ratio after 200 min of mechanical ventilation. (B ) Whole respiratory system compliance after completion of the experiment (closed chest). Each value represents mean ± SD; P < 0.05 and *versus  low-tidal volume ventilation, #versus  high-tidal volume ventilation. The table below the figures depicts the experimental groups, ventilatory regime, and treatment strategies. Numbers within error bars  depict sample size. Allo = allopurinol; C-PTIO = 2-(4-carboxyphenyl)-4,5dihydro-4,4,5,5-tetramethyl-1H-imidazolyl-1-oxy-3oxide; L-NAME = N^ω-nitro-L-arginine methyl ester; NaNO²= sodium nitrite; NO = nitric oxide; V^T= tidal volume.