Fig. 1. Characterization of the peritoneal metastasis model. Photon-counting analysis of peritoneal dissemination after the intraperitoneal inoculation of 60As6 Luc cells. Scid mice bearing 60As6Luc tumors in the abdominal cavity were anesthetized and subjected to observations after intraperitoneal administration of luciferin (A ). Quantitative analysis of the progression of peritoneal disseminated metastasis of tumor cells (n = 5). This experiment was repeated three times, and similar results were observed each time (B ). Macroscopic evidence of peritoneal dissemination in scid mice bearing tumor cells. There were metastatic lesions in the intestine (C , arrowheads ) and the parietal peritoneum (D , arrowheads ). Scale bar: 10 mm.