Fig. 8. Size distribution of polychronous groups that activate at baseline and under varying degrees of γ-aminobutyric acid receptor type A (GABAA) receptor potentiation and input frequency reduction. The direct and indirect effects of increased GABAA-mediated inhibition consistent with plasma propofol concentrations associated with general anesthesia skew the distribution toward those groups containing a smaller number of neurons. *P < 0.02 versus baseline.