Fig. 3. Relationship between mean values of cardiac output and right ventricle end-systolic pressure (RVESP) of the three different concentrations of each inhalation agent during control (triangles ) and after monocrotaline pretreatment (circles ). Lines  represent linear correlations with a zero axis intercept of grouped means during isoflurane (Iso; red symbols ), desflurane (Des; blue symbols ), and sevoflurane (Sevo; green symbols ) inhalation for control (solid lines ) and monocrotaline pretreatment values (dashed lines ). Note the steepening of this relationship with monocrotaline denoting increased pulmonary vascular resistance, particularly with desflurane. Data points represent mean ± SD of 12 animals (control group) or 11 animals (monocrotaline group).