Fig. 4. Comparison of the changes of the specific and nonspecific thalamocortical functional connectivities across the states of consciousness. A , The reduction ratio wakeful baseline to deep sedation. B , The increase ratio from deep sedation to recovery. C , The increase ratio from wakeful baseline to recovery. D , Comparison of the extent of functional connectivity between the left and right hemispheres in the three states of consciousness for the specific system. E , The same for the nonspecific system. Note the hemispheric asymmetry of connectivity in deep sedation. *P < 0.05, **P < 0.01, ***P < 0.001, paired t test via a leave-one-out test analysis with error bars indicating SD.