Fig. 2. Resuscitation with stored erythrocytes is associated with a reduced survival rate in high-fat diet–fed mice. Standard-diet–fed (A, B ) or high-fat diet–fed (C, D ) mice were subjected to 90 min of hemorrhagic shock and resuscitated with either fresh erythrocytes (n = 10, stored for <24 h) or stored erythrocytes (n = 10, stored for 2 weeks). An additional group of high-fat diet–fed mice (n = 10) was resuscitated with stored erythrocytes, while breathing 80 parts per million nitric oxide from 10 min before resuscitation until 2 h after resuscitation. Data are expressed as percent survival (%). **P < 0.01 differs versus  fresh erythrocytes, †P < 0.05 differs versus  stored erythrocytes. iNO = inhaled nitric oxide (80 parts per million).