Fig. 3.
(A) Median plot of mean arterial pressure (10 mg/kg bupivacaine infusion at t = 0). Response to four different intravenous infusions starting at t = 30 s: 4 ml/kg 30% intravenous lipid emulsion (ILE30), 4 ml/kg 20% ILE (ILE20), 4 ml/kg 0.9% saline (saline), and no treatment (null). (B) Plot of time points when rate–pressure product is different from baseline (P < 0.05) based on paired Mann–Whitney U test with 1-s time scale for 30% ILE, 20% ILE, saline, and null. (C and D) Same as A and B, but for median heart rate. (E and F) Same as A and B but for median rate–pressure product normalized to baseline (averaged over 20s before bupivacaine infusion). (G and H) Same as A and B, but for carotid blood flow normalized to baseline (averaged over 20s before bupivacaine infusion).

(A) Median plot of mean arterial pressure (10 mg/kg bupivacaine infusion at t = 0). Response to four different intravenous infusions starting at t = 30 s: 4 ml/kg 30% intravenous lipid emulsion (ILE30), 4 ml/kg 20% ILE (ILE20), 4 ml/kg 0.9% saline (saline), and no treatment (null). (B) Plot of time points when rate–pressure product is different from baseline (P < 0.05) based on paired Mann–Whitney U test with 1-s time scale for 30% ILE, 20% ILE, saline, and null. (C and D) Same as A and B, but for median heart rate. (E and F) Same as A and B but for median rate–pressure product normalized to baseline (averaged over 20s before bupivacaine infusion). (G and H) Same as A and B, but for carotid blood flow normalized to baseline (averaged over 20s before bupivacaine infusion).

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