Survival rate during the first 10 days after cardiac arrest and cardiopulmonary resuscitation (CA/CPR). TH + iNO 30 min after ROSC = wild-type (WT) mice that were subjected to CA/CPR and treated with therapeutic hypothermia (TH) combined with inhaled nitric oxide (iNO) at 40 ppm starting 30 min after return of spontaneous circulation (ROSC). TH + iNO 2 h after ROSC = WT mice that were subjected to CA/CPR and treated with TH combined with iNO at 40 ppm starting 2 h after ROSC. TH + iNO 6 h after ROSC = WT mice that were subjected to CA/CPR and treated with TH combined with iNO at 40 ppm starting 6 h after ROSC. TH alone = WT mice that were treated with TH after CA/CPR. NT = WT mice that were maintained at normothermia for 24 h after CA/CPR. N = 9, 9, 7, 51, and 5 respectively. *P < 0.05 versus TH alone. #P < 0.05 versus NT. Differences in survival rates were analyzed with log-rank test.