Fig. 2.
Treatment-related factors. (A) Labor induction. Induced labor is associated with more pain in early labor. The simulations were calculated for 24-yr-old parturients (median age) with the common ADRB2 genotype (rs1042714) allele (CC), without oxytocin or artificial rupture of membranes. (B) Augmentation and rupture of membranes. Labor that is augmented with oxytocin becomes painful more quickly. Rupture of membranes is also associated with more rapid development of pain. The simulations were calculated for 24-yr-old parturients (median age) with the common ADRB2 genotype (rs1042714) allele (CC), without induction of labor. AROM = artificial rupture of membranes; NRS = numerical rating score for pain.