Fig. 2.
Fiber cross-sectional area in diaphragm skeletal muscle myofibers expressing myosin heavy chain (MHC) I (type I), MHC IIa (type IIa), and MHC IIx/IIb (type IIx/IIb) (CON: n = 7; MV: n = 8; MV + epoxomicin: n = 8). Values are mean ± SD. *Significantly different versus CON (P < 0.0167). Exact P values for all comparisons are listed below the graph. Acutely anesthetized control animals (CON); 12-h mechanically ventilated animals, no treatment (MV); 12 h of MV, treatment with the proteasome inhibitor epoxomicin (MV + epoxomicin).