Long-lasting mechanical hypersensitivity in fracture/cast mice. Fracture/cast mice display long-lasting mechanical hypersensitivity on the ipsilateral hind paw 14 weeks after fracture (A). No significant differences in mechanical sensitivity were observed in the contralateral hind paw for any of the groups (B). **P < 0.01, ***P < 0.001. n = 8 (control) and n = 11 (fracture/cast). Errors bars = SEM.