Fig. 5.
(A–F) Observed/predicted plasma dexmedetomidine concentrations versus time for existing pharmacokinetic models. (G–L) Observed versus predicted plasma dexmedetomidine concentrations for existing pharmacokinetic models. The black lines are Loess smoothers. COBS = observed (measured) plasma concentration; CPRED = population-predicted plasma concentration.

(A–F) Observed/predicted plasma dexmedetomidine concentrations versus time for existing pharmacokinetic models. (G–L) Observed versus predicted plasma dexmedetomidine concentrations for existing pharmacokinetic models. The black lines are Loess smoothers. COBS = observed (measured) plasma concentration; CPRED = population-predicted plasma concentration.

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