Blood glucose concentrations over time in the various experimental groups (A). MB fraction of creatine kinase (CK-MB) concentrations (B) and infarct size as percentage of the area at risk (C). Data are presented as mean ± SD. AAR = area at risk; HG + Diaz = hyperglycemia + diazoxide; HG + I/R = hyperglycemia + ischemia–reperfusion; HG + ISO = hyperglycemia + isoflurane postconditioning; HG + ISO + Diaz = diazoxide administration to isoflurane-postconditioned rabbits in the presence of hyperglycemia; I/R = ischemia–reperfusion; ISO = isoflurane postconditioning. **P ≤ 0.01 compared with the I/R group; ***P ≤ 0.001 compared with the I/R group; #P ≤ 0.05 compared with the HG + ISO group; ##P ≤ 0.01 compared with the HG + ISO group.