Fig. 5.
Hepatic hepcidin knockdown mice show enhanced oxidative status 24 h after CLP. (A, B) The mRNA levels of NADPH oxidases and the activity of NADPH oxidases in the liver were measured as described in the Materials and Methods section (n = 5). (C) The mRNA levels of antioxidant proteins in the liver were also measured (n = 5). *P < 0.05; **P < 0.01. Cat = catalase; CLP = cecal ligation and puncture; mRNA = messenger RNA; NADPH = nicotinamide adenine dinucleotide phosphate; Prdx3 = peroxiredoxin 3; SOD = superoxide dismutase.