Sensitivity analyses in selected prespecified populations. Models included all variables in table 4 except the interaction with age. Hazard ratios and 95% CIs are plotted on a logarithmic scale. Source data are given in appendix 2. Hazard ratios in sensitivity analyses were generally consistent with those found in the whole cohort. Severity of patient illness, surgical factors, concurrent medication use, and angiotensin receptor blocker (ARB) resumption timing did not seem to greatly affect the hazard ratios. All estimates were statistically significant except when analysis was restricted to those that resumed angiotensin- converting enzyme inhibitor, which resulted in a small sample size and wide CI. *P < 0.001, †P < 0.01. ASA = American Society of Anesthesiologists; GI = gastrointestinal; POD = postoperative day.